I recently viewed a webinar video replay:
"The Skinny on Obesity" with Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. He argues that fructose (too much) and fiber (not enough) appear to be cornerstones of the obesity epidemic through their effects on insulin. Series: UCSF Mini Medical School for the Public [7/2009] [Health and Medicine] [Show ID: 16717]
Dr. Lustig is a very captivating and well-versed pediatrician, in this video he reveals that, according to his research and clinical observations, the major contributors to obesity today are not sedentary, gluttonous habits; neither is calorie restriction and exercises a cure.
Obesity is a consequence of modernized, enhanced, altered packaged food, that is launched at us everywhere we look, in every modern city in the world; peddling multi-sugars & diet sodas (Coke, Pepsi, Sprite, etc), low-fat, and high carbohydrate “menu of the day” items for your “grab and go” lifestyle.
Paying no mind to the act of providing fuel/food for your miraculous self-healing body/mind, with a quality source of energy that prevents gene expression of degenerative diseases, and increases the body’s ability to become chemically and immune tolerant to living in this modern world, a requirement for optimal human performance.
What choice does one have?
Fortunately, there are two things we can control that serve to enhance healthy protein duplication and preserve the vital internal environment needed to sustain a healthy functional body/mind; food as medicine and our thoughts, words, and actions towards self and others. The science of Epigenetics is at the forefront of this research manifesting itself daily. (12) (13) (14)
The choice in food, in my opinion, is a keto-adaptive lifestyle. Since introducing that way of life into my journey for health and wellness, all objective and subjective findings have manifested a better state and quality of life that is improving daily. I am also finding similar results in those patients I have recommended this path to.
The literature attests to the beneficial effects nutritional ketosis has on: metabolic syndromes, insulin resistance, PCOS, Diabetes Type 2, Hypoglycemia, or any other disruption of insulin metabolism. (11) (3) (8)
When it comes to thoughts, words, and actions the importance of intimacy, touch, and community is also vital in providing healthy functional expression of the immune system and brain/nervous system.
The frequency and vibration of each word and touch affects the expression of our genes.
With a 1-2 punch from dietary and cognitive lifestyle changes, the outcomes are up to each and every person as to whether inherited gene markers are expressed or not. In the end, the buck stops here with each and everyone of us, and the choices we make daily.
The application of ketogenic diets is not an easy achievable task to counsel potential patients on, as it takes a herculean effort to adapt into, especially when there is health, lifestyle, degenerative progression, and the stress of modern life to contend with, at the same time a person is implementing a new, rigorous, and seemingly counterintuitive lifestyle change. Which requires utmost focus and self–responsibility.
A patent has now been developed, which was prompted by the US NAVY seeking a nutritional source of exogenous ketones for Navy Seals, at the University of Florida by Dominic D'Agostino, in order to increase brain endurance for deep sea diving, without the onset of seizure activity.
The benefits of ketogenic diets are profound and are palliative to the most significant pandemic causes of degenerative diseases today:
1. Anti-inflammatory properties (6)
2. Protects the Pancreas by sparing the use of Insulin, preventing Diabetes, Hypoglycemia and Metabolic Syndrome (3) (8)
3. Are neuro-protective and neurotrophic, preventing brain and nervous system degeneration (2) (7) (9) (10)
4. Promotes increased oxygenation, which is protective to all cellular tissues (4)
5. Improves ATP production at the mitochondrial level (4) (12)
6. Aids in the Repair of DNA by preventing cancer (6) (4) (12)
7. Slows aging by promoting elongations of telomeres
8. Increases Glutathione production vital for Liver, Brain and Gut protection (12)
9. Cardio-protective by increasing HDL, reducing LDL, VLDL (11)
The ability to implement a ketogenic lifestyle has become 1000 times easier since this exogenous ketone supplement product has arrived on the scene. It successfully induces nutritional ketosis within 20-40 min of consuming it.
Once the brain and body receive the message to be in ketosis to provide cellular energy, the process of adaptation can then be undertaken one individual at a time, for a lifetime.
The other piece is utilizing genetic information from each patient to determine the best course of action on treatment and lifestyle changes, to set in motion the prevention of expressing the dreaded familial inheritance of our ancestors and their habits.
Genetic marker tests are now offered by various labs, when a physician can provide these objective findings to the general population walking into our offices daily, along with lifestyle and dietary coaching, then a real impact can be made on the outcomes for patient care and the prevention of all degenerative diseases.
So the recipe for Obesity is to educate and implement the myriads of tools available to empower and assist each person, in order to doctor them towards a healthy quality of body/mind, for the rest of their lives. The life saving and economic impact of these practices is profound.
In my opinion, this is now the most viable way to develop strategies that lead to treatment protocols prescribed, making the biggest impact on the quality of their life for optimal health and wellness, on this planet today.
I believe that this lifestyle is the foundation for delivering a journey for optimal human performance instead of the current pandemics extant on this planet today, which looms larger daily.
I invite my colleagues to perform due diligence on this subject and change old paradigms that no longer deliver health but rather an outdated “sick care” “this for that model”.
3. Orphanet J Rare Dis. 2015 Sep 24;10(1):120.doi:10.1186/s13023-015-0342-6. Ketogenic diet in a patient with congenital hyperinsulinism: a novel approach to prevent brain damage. Maiorana A1, Manganozzi L2, Barbetti F3, Bernabei S4, Gallo G5, Cusmai R6, Caviglia S7, Dionisi-Vici C8.
4. Int J Biochem Cell Biol. 2015 Jun;63:55-9. doi: 10.1016/j.biocel.2015.01.022. Epub 2015 Feb 7. Mitochondria: The ketogenic diet--A metabolism-based therapy. Vidali S1, Aminzadeh S1, Lambert B2, Rutherford T2, Sperl W3, Kofler B4, Feichtinger RG1.
5. Cancer Res. 2014 Dec 1;74(23):6991-7002. doi: 10.1158/0008-5472.CAN-14-0385. Epub 2014 Oct 10. Long-chain fatty acid analogues suppress breast tumorigenesis and progression. Gluschnaider U1, Hertz R1, Ohayon S1, Smeir E1, Smets M1, Pikarsky E2, Bar-Tana J3.
6. Nat Med. 2015 Mar;21(3):263-9. doi: 10.1038/nm.3804. Epub 2015 Feb 16. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Youm YH1, Nguyen KY1, Grant RW2, Goldberg EL1, Bodogai M3, Kim D4, D'Agostino D5, Planavsky N6, Lupfer C7, Kanneganti TD7, Kang S8, Horvath TL1,Fahmy TM4, Crawford PA9, Biragyn A3, Alnemri E8, Dixit VD10.
8. Can J Diabetes. 2014 Aug;38(4):223-4. doi: 10.1016/j.jcjd.2014.05.002. Epub 2014 Jul 9. The ketogenic diet for the treatment of myoclonic astatic epilepsy in a child with type 1 diabetes mellitus. Aylward NM1, Shah N2, Sellers EA3.
9. BMC Neurosci. 2006 Apr 3;7:29. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. Zhao Z1, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM.
10. J Lipid Res. 2014 Dec;55(12):2450-7. doi: 10.1194/jlr.R046706. Epub 2014 Apr 10. The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury. Prins ML1, Matsumoto JH2.
11. Nutr Metab (Lond). 2005 Dec 16;2:35. The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot study. Mavropoulos JC1, Yancy WS, Hepburn J, Westman EC. Author information1 Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
12. J Pediatr Gastroenterol Nutr. 2015 Nov 26. [Epub ahead of print] Epigenetics in Paediatric Gastroenterology, Hepatology and Nutrition - Current Trends and Future Perspectives. Zilbauer M1, Zellos A, Heuschkel R, Gasparetto M, Kraiczy J, Postberg J, Greco L, Auricchio R, Galatola M, Embleton N, Wirth S, Jenke A.
13. Proc Nutr Soc. 2014 May;73(2):289-301. doi: 10.1017/S002966511300387X. Epub 2014 Jan 10. The impact of early nutrition on the ageing trajectory. Tarry-Adkins JL1, Ozanne SE1.
14. Br J Nutr. 2014 Dec 14;112(11):1850-7. doi: 10.1017/S0007114514002827. Epub 2014 Oct 20. DNA methylation: the pivotal interaction between early-life nutrition and glucose metabolism in later life. Zheng J1, Xiao X1, Zhang Q1, Yu M1.