Excess Vitamin D: Too Much of A Good Thing - Part Three

Excess Vitamin D: Too Much of A Good Thing - Part Three

As long as medicine continues to rely on dried blood analysis (vs. live blood analysis), it is beneficial to look at both biomarkers in the blood; the active and inactive forms of vitamin D, as well as vitamin D binding protein, kidney function tests, and other hormone testing (Parathryoid hormone, thyroid hormone, antibodies, enzymes, etc).

1, 25 (OH) Active
25 (OH) Inactive
vitamin D binding protein
Parathyroid hormone and other hormones
Testing only for the inactive form does not reveal the big picture. If inactive 25-D preferentially binds to VDR receptor sites, there is not enough information to know if there is a conversion problem or if active 1,25D is blocking other hormonal receptors based on artificial supplementation of vitamin D.

Patients with Th1 inflammation (who have not been supplementing with vitamin D) often have a low level of 25-D while the level of 1,25-D is high. Testing only 25-D, as is usually done, may result in a false diagnosis of vitamin D deficiency.

Low levels of 1,25 (active) D may also indicate kidney dysfunction if the kidneys are unable to activate inactive 25-D to active 1,25-D. While most people assume a high amount of 1, 25-D is best, high levels may indicate parathyroid disease, sarcoidosis, rheumatoid arthritis, fibromyalgia, Lyme disease and other inflammatory autoimmune conditions.

Prevention and treatment of autoimmune conditions and cancer in the medical community uses a patent for biologically active vitamin D compounds  in combination with at least one other immunomodulatory compoundsuch as interleukin-10, interleukin-4, or a TNF.alpha. inhibitor. The patented drug Benicar is used as the core drug in the Marshall Protocol, developed by Trevor Marshall.  Similarly, patented L-carnosine salt used to treat and prevent inflammatory bowel disease. However, be aware that these patented drugs may have a limited effect due to the side effects of any drug therapy, which are not natural to the body and ultimately cause congestion in the blood and various organs.

Rosemary appears to be the natural option to Benicar because it contains L- carnosine, which is a powerful VDR antagonist. L-carnosine in rosemary, sage, oregano, and other herbs acts as an anti-oxidant, chelator of copper cations, prevents protein glycation, is a pH buffer, and has a rejuvenating effect. Meat is the natural dietary source of carnosine.


Here is 1,25D as it docks into the VDR with the superimposition of carnosic acid (color) contained in rosemary and sage. A pure source of Rosemary can be found here.

Variations in polymorphisms in the VDR may alert the need for additional nutritional support. For instance, the defect at the gene position VDR Fok + can impact vitamin D levels. Research shows that supplementing vitamin D may be beneficial. Sage and rosemary support vitamin D receptors. It may be necessary to support the pancreas when having a VDR Fok + mutation using vitamin and digestive/pancreatic enzymes.

Secosteroid “vitamin” D is an epigenetic innovator. Without a full understanding of the “sunshine vitamin,” we should be careful in promoting solutions that may actually be driving disease manifestation higher in the population.

Like nature, our bodies are homeostatically regulated, meaning that our intricate metabolic system through the cells compensate for environmental changes by making the appropriate internal changes in order to restore balance.  Just as body temperature, blood glucose, and countless other internal variables are self-regulated, so is vitamin D metabolism. And these cellular changes are driven by our innate and adaptive immune systems which are driven at the level of our cells (via receptors such as VDR, CD-R) by cytokines that summon and cause the creation of our macrophages to defend health.

The alternate hypothesis – that vitamin D serum levels are modified by disease processes – is far more compelling than the currently accepted ‘vitamin’ ideology – that the lower levels observed in sick individuals are indicative of a nutritional deficiency.

We must address the Candida and Lyme disease that underlies D-deficiency if the body is to rebalance itself. For Lyme disease or any disease to manifest, they depend on the conditions of the body’s terrain (pH, nutritional status, toxicity). The imbalance of normal flora results from an acidic gut environment that results from an acidic intestine that results from leaky gut. An excess of acid in the body and an acidic intestinal tract can come from decreased liver function from an accumulation of toxins from food, air, water, amalgams, vaccines, drugs, and a poor diet.

If our bugs tell us anything it is to remind us that the best we can do for the body is to provide it the tools of nature, starting with being out in nature. Sunshine is the best remedy for D balance.

Our bodies also require the right fuel from whole, fresh raw, fermented, pastured, healing foods, foods as close to the earth as possible. Foods and herbs in their original packages, naturally balanced in nutrients (fish liver oils), live foods, rich vitamins, minerals, fats, carbohydrates, proteins, and bacteria. Foods that heal the gut (bone broths). We must select foods, and food-based supplements, for their hermetic ability to modulate optimal levels of vitamin D and other hormones in the body. Of these, cod liver oil, preserved naturally with rosemary oil, is an excellent form that the body naturally utilizes.

Frequency technologies are proving beneficial in addressing yeast and Lyme toxicity. Lyme disease is most easily helped by Cannabis oil or homeopathic cannabis remedies. Cannabis has its own endocannabinoid receptors throughout the body, indicating the body’s natural affinity for a plant nature provides. Working with the body on an energetic level (including lasers) is the next frontier, especially when artificial hormone supplementation offers no decrease in chronic disease rates.

Along with a nutrient-dense diet, adequate rest, and following your passion, the best way to ensure optimal vitamin D levels, naturally, is to follow the sun and allow your body’s wisdom to lead the way to health.

*Special thanks to Jim Stephenson Jr for the invaluable assistance in collecting the studies.